Lcariside I

Lcariside I - Names and Identifiers

Name	Anhydroicaritin-7-O-glucoside
Synonyms	Icariin I Lcariside I 56725-99-6Icariside I Anhydroicaritin-7-O-glucoside Icariin Impurity 1 (Icariside I) 7-(β-D-Glucopyranosyloxy)-3,5-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3,5-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)- 3,5-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
CAS	56725-99-6

Lcariside I - Physico-chemical Properties

Molecular Formula	C27H30O11
Molar Mass	530.52
Density	1.475±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	252-253℃
Boling Point	801.3±65.0 °C(Predicted)
Specific Rotation(α)	-28.4 (Py)
Solubility	DMSO, methanol
Appearance	Yellow powder or crystal
pKa	6.04±0.40(Predicted)
Storage Condition	2-8°C
MDL	MFCD01662755
Physical and Chemical Properties	Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from epimedium.

Lcariside I - Reference

Reference

1. Ju Jing, Pan Yuzheng, Peng Ling Ling, Luo Yan. Effects of icariside Ⅱ on sIgA, rBD2 and IL-6 in rats with tracheal intubation [J]. Chinese medical journal, 2019,34(06):1235-1238.
2. Yang Yishun, Zhang Tong, Ding Yue et al. Preparation and HPLC Determination of three icariin secondary products [J]. Chinese patent medicine 2020 042(003):779-782.
3. Caihong Wang, Caishen Wu, Jinlan Zhang, Ying Jin, Systematic considerations for a multicomponent pharmaco kinetic study of Epimedii wushanensis herba, 2015, P
4. Liu, Congyan, et al. "Icariin combined with snailase shows improved intestinal hydrolysis and absorption in osteoporosis rats." Biomedicine & Pharmacotherapy 94 (2017): 1048-1056.https://doi.org/10.1016/j.biopha.2017.07.163
5. Zhou, Jing, et al. "A strategy for rapid discovery of traceable chemical markers in herbal products using MZmine 2 data processing toolbox: A case of Jing Liqueur." Chinese Herbal Medicines (2021).

Lcariside I - Reference Information

biological activity	Icariside I (Icarisid I) is one of the main components of Epimedii Folium, can significantly stimulate cell proliferation and osteoblast differentiation.
Use	icariside I has the function of improving cardiovascular system function, regulating endocrine and enhancing immunity. for content determination/identification/pharmacological experiments. Pharmacological Efficacy: estrogen-like effects

Last Update：2024-04-09 21:04:16